Matt Damon 
 as Jason Bourne

Julia Stiles 
 as Nicky Parsons

David Strathairn 
 as Noah Vosen

Scott Glenn 
 as CIA Director Ezra Kramer

Paddy Considine 
 as Simon Ross

Edgar Ramírez 
 as Paz

Albert Finney 
 as Dr. Albert Hirsch

Joan Allen 
 as Pamela Landy

Tom Gallop 
 as Tom Cronin

Corey Johnson 
 as Conrad Wills

Daniel Brühl 
 as Martin Kreutz

Joey Ansah 
 as Desh Bouksani

Colin Stinton 
 as Neal Daniels

Dan Fredenburgh 
 as Jimmy

Lucy Liemann 
 as Lucy

Bryan Reents 
 as Technician

Arkie Reece 
 as Technician

John Roberson 
 as Technician

Russ Huards 
 as Technician

Mark Bazeley 
 as Betancourt

Sinead O'Keeffe 
 as Chamberlain

Charles Venn 
 as Agent Hammond

Scott Adkins 
 as Agent Kiley

Branko Tomović 
 as Russian Policeman

Laurentiu Possa 
 as Russian Policeman

Trevor St. John 
 as Tactical Team Leader

Albert Jones 
 as Tactical Team Agent

Jeffrey Lee Gibson 
 as Vosen's Driver

Uriel Emil Pollack 
 as Morgue Attendant

Omar Hernández 
 as NYPD Officer

William H. Burns 
 as NYPD Officer

Michael Wildman 
 as CRI Agent

Kai Martin 
 as Hoody

Michael Ahl 
 as Businessman (uncredited)

Alex Argenti 
 as Witness to a Murder (uncredited)

Martin Ballantyne 
 as Commuter (uncredited)

Arthur Benjamins 
 as Senator (uncredited)

David Boston 
 as Businessman on Street (uncredited)

Glynis Brooks 
 as Senator Gillham (uncredited)

Mahmud Chowdhury 
 as Train Commuter (uncredited)

James Ciccone 
 as Construction Worker (uncredited)

Casey Cipriani 
 as Girl at Hot Dog Stand (uncredited)

Brian Cox 
 as Ward Abbott (voice) (archive footage) (uncredited)

Julie Eagleton 
 as Commuter (uncredited)

Richard El Khazen 
 as Police Officer (uncredited)

Ronald E. Giles 
 as Commuter (uncredited)

Ilan Krigsfeld 
 as Decoy Bystander (uncredited)

Kirk Lambert 
 as Attorney (uncredited)

Chris Mansfield 
 as Commuter (uncredited)

Bill Massof 
 as CRI Agent (uncredited)

Luis Mottola 
 as Mob (uncredited)

Mark Mottram 
 as Special Agent in Car (uncredited)

Karl Olsen 
 as CIA Sub-station Chief (uncredited)

Jose Pecino 
 as Station Commuter (uncredited)

Franka Potente 
 as Marie Helena Kreutz (archive footage) (uncredited)

Walter A. Saunders III 
 as Security Guard (uncredited)

James Schram 
 as Hospital Patient (uncredited)

Mark Shrimpton 
 as British Intelligence Officer (uncredited)

Tina Simmons 
 as Businesswomen (uncredited)

Brian Smyj 
 as Agent (uncredited)

John Snowden 
 as News Agent

Albert Tang 
 as Underground Passenger (uncredited)

Paul Thornton 
 as Passer-by (uncredited)

Anthony Wanzer 
 as Police Officer (uncredited)

John Warman 
 as Policeman (uncredited)

Chris Wilson 
 as Commuter (uncredited)

Simon John Wilson 
 as Commuter (uncredited)

Ben Youcef 
 as Nabile (uncredited)

Sebastian Feldman 
 as Buenos Aires Cafe Patron (voice) (uncredited)