Chris Pine 
 as Captain James T. Kirk

Zachary Quinto 
 as Commander Spock

Zoe Saldaña 
 as Leuitenant Nyota Uhura

Benedict Cumberbatch 
 as John Harrison / Khan

Karl Urban 
 as Dr. Leonard 'Bones' McCoy

Simon Pegg 
 as Lieutenant Commander Montgomery 'Scotty' Scott

Bruce Greenwood 
 as Admiral Christopher Pike

Peter Weller 
 as Admiral Alexander Marcus

Alice Eve 
 as Dr. Carol Marcus

Anton Yelchin 
 as Ensign Pavel Chekov

John Cho 
 as Lieutenant Hikaru Sulu

Leonard Nimoy 
 as Ambassador Spock

Noel Clarke 
 as Thomas Harewood

Nazneen Contractor 
 as Rima Harewood

Amanda Foreman 
 as Ensign Brackett

Jay Scully 
 as Lieutenant Chapin

Jonathan Dixon 
 as Ensign Froman

Aisha Hinds 
 as Navigation Officer Darwin

Joseph Gatt 
 as Science Officer 0718

Jeremy Raymond 
 as Lead Nibiran

Tony Guma 
 as Nibiran

Kimberly Arland 
 as Madeline

Sean Blakemore 
 as Klingon

Nick E. Tarabay 
 as Klingon

Beau Billingslea 
 as Captain Abbot

Deep Roy 
 as Keenser

Anjini Taneja Azhar 
 as Lucille Harewood

Jack Laufer 
 as Doctor

Katie Cockrell 
 as Girl

Kellie Cockrell 
 as Girl

Jason Matthew Smith 
 as Cupcake

Seth Ayott 
 as U.S.S. Enterprise Shuttle Ensign

Marco Sanchez 
 as Torpedo Security

Lee Reherman 
 as Uniformed Mercenary

Scott Lawrence 
 as U.S.S. Vengeance Officer

Usman Ally 
 as U.S.S. Vengeance Officer

Nolan North 
 as U.S.S. Vengeance Bridge Officer

James Hiroyuki Liao 
 as U.S.S. Vengeance Bridge Officer

Rob Moran 
 as U.S.S. Vengeance Ensign

Berit Francis 
 as Starfleet Admiral

Akiva Goldsman 
 as Starfleet Admiral

Benjamin P. Binswanger 
 as Starfleet Admiral

Christopher Doohan 
 as Transport Officer

Andy Demetrio 
 as U.S.S. Enterprise Bridge Crew

Gianna Simone 
 as U.S.S. Enterprise Bridge Crew

Rene Rosado 
 as U.S.S. Enterprise Bridge Crew

Jacqueline King 
 as U.S.S. Enterprise Bridge Crew

Long Tran 
 as U.S.S. Enterprise Bridge Crew

Ningning Deng 
 as U.S.S. Enterprise Bridge Crew

Jodi Johnston 
 as U.S.S. Enterprise Bridge Crew

Colleen Harris 
 as Lady V

Jeff Chase 
 as U.S.S. Enterprise Security

Monisola Akiwowo 
 as U.S.S. Enterprise Nurse

Paul K. Daniel 
 as Shuttle Pilot

Ser'Darius Blain 
 as U.S.S. Enterprise Red Shirt

Heather Langenkamp 
 as Moto

David C. Waite 
 as U.S.S. Enterprise Crew

Melissa Paulo 
 as Bar Girl

Cynthia Addai-Robinson 
 as San Francisco Woman

Drew Grey 
 as San Francisco Bar Patron

Douglas Weng 
 as U.S.S. Vengeance Security

Charlie Haugk 
 as San Francisco Resident

Max Chernov 
 as San Francisco Resident

Marc Primiani 
 as San Francisco Resident

Jesper Inglis 
 as San Francisco Resident

Jacob Rhodes 
 as Nibiru Child

Kentucky Rhodes 
 as Nibiru Child

Toney Wilson 
 as Shaku

Eric Greitens 
 as Starfleet Ceremonial Guard

Melissa Steinman 
 as Starfleet Ceremonial Guard

Adam McCann 
 as Starfleet Ceremonial Guard

Jon Orvasky 
 as Starfleet Ceremonial Guard

Gerald W. Abrams 
 as Starfleet Memorial Admiral

James McGrath 
 as Starfleet Memorial Admiral

Brian T. Delaney 
 as Additional Voices (voice)

Arlen Escarpeta 
 as Additional Voices (voice)

Joe Moses 
 as Additional Voices (voice)

Kevin Michael Richardson 
 as Additional Voices (voice)

David Sobolov 
 as Additional Voices (voice)

Matthew Wood 
 as Additional Voices (voice)

Fred Tatasciore 
 as Additional Voices (voice)

Kiff VandenHeuvel 
 as Additional Voices (voice)

Audrey Wasilewski 
 as Additional Voices (voice)

Bill Hader 
 as Additional Voices (voice)

Britanni Johnson 
 as NYU Nurse (uncredited)

Chris Gardner 
 as Additional Voices (voice)

Julianne Buescher 
 as Additional Voices (voice)

Joe Hanna 
 as Additional Voices (voice)

David Acord 
 as Additional Voices (voice)

Elle Newlands 
 as Additional Voices (voice)

Candice Renee 
 as Additional Voices (voice)

Emily Towers 
 as Additional Voices (voice)

Gina Hirsch 
 as Additional Voices (voice)

Tom Archdeacon 
 as Ensign Spyke (uncredited)

Jon Lee Brody 
 as U.S.S. Enterprise Security (uncredited)

Hiram A. Murray 
 as Bar Patron (uncredited)

Fernando Chien 
 as Starfleet Admiral (uncredited)