Matt Damon 
 as Jason Bourne

Julia Stiles 
 as Nicky Parsons

David Strathairn 
 as Noah Vosen

Scott Glenn 
 as CIA Director Ezra Kramer

Paddy Considine 
 as Simon Ross

Edgar Ramírez 
 as Paz

Albert Finney 
 as Dr. Albert Hirsch

Joan Allen 
 as Pamela Landy

Tom Gallop 
 as Tom Cronin

Corey Johnson 
 as Conrad Wills

Daniel Brühl 
 as Martin Kreutz

Joey Ansah 
 as Desh Bouksani

Colin Stinton 
 as Neal Daniels

Dan Fredenburgh 
 as Jimmy

Lucy Liemann 
 as Lucy

Bryan Reents 
 as Technician

Arkie Reece 
 as Technician

John Roberson 
 as Technician

Russ Huards 
 as Technician

Mark Bazeley 
 as Betancourt

Sinead O'Keeffe 
 as Chamberlain

Charles Venn 
 as Agent Hammond

Scott Adkins 
 as Agent Kiley

Branko Tomović 
 as Russian Policeman

Laurentiu Possa 
 as Russian Policeman

Trevor St. John 
 as Tactical Team Leader

Albert Jones 
 as Tactical Team Agent

Jeffrey Lee Gibson 
 as Vosen's Driver

Uriel Emil Pollack 
 as Morgue Attendant

Omar Hernandez 
 as NYPD Officer

William H. Burns 
 as NYPD Officer

Michael Wildman 
 as CRI Agent

Kai Martin 
 as Hoody

Michael Ahl 
 as Businessman (uncredited)

Glynis Brooks 
 as Senator Gillham (uncredited)

James Ciccone 
 as Construction Worker (uncredited)

Sebastian Feldman 
 as Buenos Aires Cafe Patron (voice) (uncredited)

Luis Mottola 
 as Mob (uncredited)

Mark Mottram 
 as Special Agent in Car (uncredited)

James Schram 
 as Hospital Patient (uncredited)

Brian Smyj 
 as Agent (uncredited)

Paul Thornton 
 as Passer-by (uncredited)

John Warman 
 as Policeman (uncredited)

Chris Wilson 
 as Commuter (uncredited)

Ben Youcef 
 as Nabile (uncredited)

Tina Simmons 
 as Businesswomen (uncredited)

Franka Potente 
 as Marie Helena Kreutz (archive footage) (uncredited)