Jeremy Renner 
 as Aaron Cross

Rachel Weisz 
 as Dr. Marta Shearing

Edward Norton 
 as Byer

Stacy Keach 
 as Turso

Dennis Boutsikaris 
 as Ward

Oscar Isaac 
 as Outcome #3

Joan Allen 
 as Pamela Landy

Albert Finney 
 as Dr. Albert Hirsch

David Strathairn 
 as Noah Vosen

Scott Glenn 
 as Ezra Kramer

Donna Murphy 
 as Dita Mandy

Michael Chernus 
 as Arthur Ingram

Corey Stoll 
 as Vendel

Željko Ivanek 
 as Dr. Donald Foite

Shane Jacobson 
 as Mackie

Elizabeth Marvel 
 as Dr. Connie Dowd

John Douglas Thompson 
 as Lt. Gen. Paulsen

Louis Ozawa 
 as LARX #3

David Wilson Barnes 
 as Drone Spec

Neil Brooks Cunningham 
 as Dr. Dan Hillcott

Corey Johnson 
 as Ray Wills

Michael Berresse 
 as Leonard

Alice Gainer 
 as Lean Forward MSNBC Anchor

Prue Lewarne 
 as CNN Reporter

Howard Leader 
 as MSNBC Analyst

James Joseph O'Neil 
 as Sterisyn-Morlanta Gateman

Tony Guida 
 as Dr. Benezara

Sonnie Brown 
 as Dr. Lieberburg

Robert Christopher Riley 
 as Outcome #6

Noel Wilson 
 as Neuro Luncheon MC

Jennifer Kim 
 as Outcome #4

Page Leong 
 as Mrs. Yun

Adi Hanash 
 as Outcome #1

Robert Prescott 
 as Air Force Officer

Don Guillory 
 as Drone Pilot

Patrick Vincent Marro 
 as Drone Command Guard

Ali Reza 
 as Dr. Talwar

Gita Reddy 
 as Dr. Chandra

Tom Riis Farrell 
 as Blue Lab Doctor

Steve Routman 
 as Blue Lab Doctor

Peter Gray Lewis 
 as Blue Lab Doctor

Anitha Gandhi 
 as Blue Lab Doctor

Heather Rasche 
 as Blue Lab Doctor

Natalie Bird 
 as Blue Lab Doctor

Nilaja Sun 
 as Blue Lab Doctor

Christopher Mann 
 as Lab Guard

Billy Smith 
 as Lab Guard

Murray Knudsen 
 as Alaska Airport Guard

Susan Egbert 
 as DIA Attorney

Tim Devitt 
 as FBI Honcho

Brian Poteat 
 as State Investigator

Clayton J. Barber 
 as Gene

Michael Papajohn 
 as Larry Hooper

David Leitch 
 as The Driver

Deidre Goodwin 
 as Candent Spokesperson

Laura Spaeth 
 as Walking Woman

Sam Gilroy 
 as C-Team

Rachel Black 
 as C-Team

Sharon Washington 
 as C-Team

Frank Deal 
 as C-Team

Rob Yang 
 as C-Team

Catherine Curtin 
 as C-Team

Matt Oberg 
 as C-Team

Gary Lee Mahmoud 
 as C-Team

Faye Yvette McQueen 
 as TSA Guard

Pat Battle 
 as MSNBC Anchor

Nico Bernuth 
 as Flight Attendant

Jane Jameston 
 as Flight Attendant

Roland Manansala 
 as Steri-M Guard

John Arcilla 
 as Joseph

Josh Banks 
 as Mackie's Assistant

Allen Jo 
 as Guard

Jonathan Eusebio 
 as Guard

Jon Valera 
 as Guard

Carl Villa Roman 
 as Sterival Catwalk Guard

Madeleine Nicolas 
 as Landlady

Ruby Ruiz 
 as Philippine Pharmacist

Cherry Devera 
 as Crisis Translator

Julienne Orindain 
 as TV Girl

Antonette Garcia 
 as TV Mom

Sonny Tuazon 
 as Manila Cop

Normandy Bacaltos 
 as Manila Cop

Edgar Letran 
 as Manila Cop

Alvin Zalamea 
 as Manila Cop

Spencer Sano 
 as Manila Cop

Julie Ysla 
 as Woman with the Bag

Joel Torre 
 as Citrus Samaritan

Ermie Concepcion 
 as Pissed Off Guy

Art Acuña 
 as Manila Driver

Adrian Talinga 
 as Captain's Son

Lou Veloso 
 as Captain

Ian Blackman 
 as Landy's Attorney

Jodi Applegate Kay 
 as Landy Reporter

Tony Carlin 
 as Landy Reporter

Karen Pittman 
 as Landy Reporter

Ana Berry 
 as Landy Reporter

Matthew J. Walters 
 as Landy Reporter

Brian O'Neill 
 as Landy Reporter

Paddy Considine 
 as Simon Ross (archive footage) (uncredited)

Sheena Colette 
 as Candent Woman #2 (uncredited)

Alexis Molnar 
 as Hotel Teen Girl (uncredited)

Courtney Hart 
 as Market Shopper (uncredited)